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KMID : 1024420210250040354
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Food Engineering Progress
2021 Volume.25 No. 4 p.354 ~ p.361
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Effect of Mushroom-Garlic Mixed Extract on Bioactivity and Immune Enhancement
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Sohn Jun-Youn
Na Haeng-Yo
Sohn Jeong-Sun
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Abstract
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As the world becomes an aging society, various geriatric diseases are induced, posing a tremendous social burden. For the development of healthy food, mushrooms and garlic, which are natural medicinal resource materials, and their mixed extracts were prepared, while the contents of general components, β-glucan, free sugar, and organic acid, were confirmed. In the case of garlic, the contents of alline and heavy metals were confirmed. The presence or absence of toxicity in each sample was checked through MTT assay in vitro, while the appropriate treatment concentration was established to confirm each extract's immune activation and anticancer effects. As a result of examining the anticancer effect from the thymus and lymph node cells of experimental mice administered orally, each extract in vivo confirmed that the CD4 T cells of thymocytes and lymph node cells were increased at all concentrations of the mixed two extracts, and they exhibit immunity activation and anticancer properties.
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KEYWORD
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mushroom, garlic, mixed extracts, immune activation
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